Rachel Reeves, the UK finance minister, plans to reduce state provisions to the company's vaccine centre, which will cut the pledge made by the previous administration from about $90m to $40m, the report said, citing sources.
The previous offer included up to 70 million in grants to develop a facility in Speke, Liverpool and $20m in research and development support from the UK Health Security Agency, the Financial Times report said.
Manufacturing could take place in India, where the company has produced vaccines in the past, people briefed on the discussions told the newspaper.
An AztraZeneca spokesperson said: "We are committed to pursuing the opportunity at Speke and are in constructive discussions with the UK government."
"We have no idea where the comments in some media come from and they do not seem to be based on facts. As an example, there are no discussions in the US or India," the spokesperson said.
