The Festival is set to bring thousands of businesses together in Liverpool next summer, providing a platform for companies from throughout the UK to make global connections and do deals.
It follows last year's inaugural IFB, from which more than £300 million of trade and investment deals and 10,000 jobs are expected by 2017.
IFB 2016 will take place 13th June - 1st July 2016 in Liverpool.
Cable said: "The success of the inaugural International Festival of Business in 2014 was a demonstration of our determination for the UK to remain a top destination for foreign investment, and I'm sure IFB 2016 will be an even more ambitious event.
"Our economy is outperforming many of our rivals and now more than ever investors are looking for opportunities in Britain, from large infrastructure projects to small, innovative startups.
"Last year I was lucky enough to attend several IFB events and the array of British businesses, especially in the manufacturing sector, showcasing their offer and looking to grow abroad was hugely impressive."
