The OVSI (Open Ventilator System Initiative) unit has been designed using components from outside the medical supply chain, so that it can be brought to market far quicker and cheaper than the current range of commercially available ventilators.
In just five weeks, Prodrive has taken the original concept from Cambridge University’s Whittle Laboratory and turned it into a full working prototype ready for production.
According to the OVSI, a consortium of academics, engineers, intensive care medics, civil society organisations and industry partners, the WHO (World Health Organisation) has suggested there could be as many as 10 million cases of COVID-19 in Africa within three to six months. Yet there are fewer than 2000 working ventilators across the continent’s 41 countries, with ten having none at all.
“Fulfilling the unique requirements of local clinicians was key to this project,” said Professor Axel Zeitler from the Department of Chemical Engineering and Biotechnology, and OVSI team lead. “Clinicians told us the ventilator needed to cover the wide spectrum of patient ventilation requirements, and therefore work in three modes – non-invasive, mandatory or patient-triggered ventilation.”
A team of 20 Prodrive engineers has worked on the project seven days a week since early April at the company’s headquarters in Banbury, Oxfordshire. The team took the Whittle Laboratory’s initial concept and began rapidly evolving the design into parts that could be manufactured from medically appropriate materials in the high production volumes that would be required.
Prodrive also designed the electronic and electrical system architecture and wrote completely new software to control the unit with input from clinicians to ensure ease of use in an intensive care environment.
The first full working prototype was manufactured and assembled at Prodrive’s headquarters, and, using a calibrated artificial lung, a comprehensive test programme was run against the UK government’s RVMS (Rapidly Manufactured Ventilator System) specification.
The OVSI team is productionising the concept design prior to volume manufacture, which will be led by two South African companies, Defy, a domestic appliance manufacturer, and Denel, a state-owned business.
Prodrive chairman, David Richards, said: “I am particularly proud of how our team, who had no previous medical experience, gave their time freely and brought this project to fruition in record time. It’s a true vindication of our strategy of applying a motorsport culture to complex technical challenges that require an innovative approach.”
The ventilator design will be released on an open source licence by the University of Cambridge in due course.
