The event, delivered by The Manufacturing Institute and sponsored by Manchester Airport's Group, will challenge teams of 13 and 14 year-olds to set up their own mini-manufacturing businesses and design, cost and market a new product.
Neil Robinson, Manchester Airport's Group CSR director, said: "As we continue to grow, we look to the workforce of the future to develop the key skills in science, engineering and maths that are so critical to employers. We are delighted to support the Make-It final as just one way we can play our part to ensure that we engage and excite the brightest young minds in the region."
This event is a culmination of a series of Make It Enterprising Challenge heats which have been sponsored by manufacturing companies across the North West including Survitec, Siemens, McBride, BAE Systems, Nuclear Management Partners and Kelloggs.
The two year-long competition has attracted 110 schools and involved almost 900 pupils and the teams competing in the Grand Final have already proved their ingenuity and initiative as winners of sub-regional heats.
On the day, teams will complete a series of manufacturing themed tasks, each taking on job roles from managing director to operations managers through to finance and sales and marketing managers.
Teams will also be tasked with developing a brand and logo for their company before pitching their ideas in a Dragons' Den-style presentation to a number of industry experts.
The Manufacturing Institute's Make It campaign aims to attract the brightest and best new talent into manufacturing by demonstrating that the sector is an exciting and rewarding career path for young people.
Since it started in 2006, over 60,000 pupils and teachers have been inspired by the campaign.